RouteBuddy, a first siting for myself, is a GPS solution for the Apple Mac. Gone are the days relying on Route 66 (which has not seen an update for many years). Routebuddy delivers one standalone app which intergrates with Garmin GPS devices (more device support to follow). Once purchased, all updates are free, with new maps available at an additional cost. Geocaching is built right into the software, with topographical data being added at a later date.
Head on over to www.routebuddy.com for the full lowdown.